SQSTM1p62 is a versatile protein that is a critical core regulator of tumor cell genetic stability, autophagy, apoptosis and other forms of cell death
We found that the autophagy receptor p62 can be oxidised leading to its oligomerisation which ultimately promotes autophagy The p62 protein, also called sequestosome 1 , is a ubiquitin-binding scaffold protein that colocalizes with ubiquitinated protein aggregates in many
luckyc4 wallet showed that p62, a chaperone protein involved in autophagy, sequestered polyubiquitinated proteins in cytoplasmic inclusion bodies in An advantage to monitoring p62 to measure autophagic flux is that lysosomal inhibitors are not necessary, because unlike LC3-II, p62 does not usually increase
