An advantage to monitoring p62 to measure autophagic flux is that lysosomal inhibitors are not necessary, because unlike LC3-II, p62 does not usually increase
p62SQSTM1 Polyclonal Antibody: For immunochemical detection of p62SQSTM1 Synonyms: Sequestosome-1, Ubiquitin-binding Protein p62 SQSTM1 then interacts with ATG8 family proteins on autophagosomes via its LIR motif, leading to p62 body recruitment to autophagosomes, followed by autophagic
เกมส์สล็อตได้เงินจริง Most nanoparticles reportedly block autophagic flux, thereby upregulating p62SQSTM1 through degradation inhibition p62 also acts as The p62 encoding gene was then isolated and termed sequestosome 1 The protein was the first adaptor involved in selective autophagy identified in